Table 2.

A list of important angiogenesis-related genes and their differential expression. Un2d: non-stabilized fractures at day 2. S2d: stabilized fractures at day 2. Un7d: non-stabilized fractures at day 7. S7d: stabilized fractures at day 7.Ctrl: unfractured legs. DE: differential expression.

Gene	Full Name	un2d/ctrl	un7d/ctrl	s2d/ctrl	s7d/ctrl	un2d/s2d	un7d/s7d
Angpt1	Angiopoietin-1	No DE	No DE	No DE	-0.82	No DE	No DE
Angpt2	Angiopoietin-2	No DE	No DE	No DE	No DE	No DE	No DE
Col18a1	Collagen, type XVIII, alpha 1	1.4	2.89	1.12	2.49	No DE	No DE
Ctgf	Connective tissue growth factor	No DE	2.36	2.69	2.09	No DE	No DE
Ecgf1	Endothelial cell growth factor-1	No DE	0.57	No DE	0.64	No DE	No DE
Edg5	Endothelial differentiation gene-5	1.18	1.19	1	0.98	No DE	No DE
Egf	Epidermal growth factor	No DE	-2.16	No DE	-1.51	No DE	No DE
Fgf2	Fibroblast growth factor-2	No DE	No DE	No DE	No DE	No DE	No DE
Fgf21	Fibroblast growth factor-21	No DE	2.2	No DE	3.64	No DE	No DE
Fgfr1	Fibroblast growth factor receptor-1	No DE	1.38	No DE	No DE	No DE	No DE
Fgfr2	Fibroblast growth factor receptor-2	No DE	1.38	No DE	No DE	-0.01	0.6
Fgfr3	Fibroblast growth factor receptor-3	No DE	2.3	No DE	No DE	-0.04	1.43
Fgfr4	Fibroblast growth factor receptor-4	No DE	2.25	No DE	1.55	No DE	No DE
Flt1	VEGFR1	No DE	-1.08	No DE	-1	No DE	No DE
Flk-1	VEGFR2	-1.03	No DE	No DE	No DE	No DE	No DE
fzd1	Frizzled-1	0.86	2.14	No DE	1.46	No DE	No DE
Hgf	Hepatocyte growth factor	0.78	0.81	0.63	1.08	No DE	No DE
Hif1a	Hypoxia inducible factor-1, alpha unit	1.87	2.08	1.7	1.61	No DE	No DE
Hif1an	Hif-1a inhibitor	-0.78	-0.81	-1.14	No DE	No DE	No DE
Mmp2	Matrix metallopeptidase 2	No DE	1.85	No DE	No DE	0.18	1.05
Timp1	Tissue inhibitor of metalloproteinase 1	4.19	4.24	4.27	4.22	No DE	No DE
Nrp1	Neuropilin1	1.58	No DE	No DE	No DE	No DE	No DE
Nrp2	Neuropilin2	1.46	1.51	0.96	1.13	No DE	No DE
Pdgfa	Platelet derived growth factor a	No DE	No DE	No DE	No DE	No DE	No DE
Pdgfc	Platelet derived growth factor b	No DE	1.51	No DE	No DE	No DE	No DE
Tgfb1	Transforming growth factor, beta 1	No DE	No DE	No DE	No DE	No DE	No DE
Tgfb2	Transforming growth factor, beta 2	-1.14	No DE	No DE	No DE	No DE	No DE
Tgfb3	Transforming growth factor, beta 3	No DE	0.92	-1.38	0.79	No DE	No DE
Tie-1	TIE tyrosine kinase	No DE	No DE	No DE	No DE	No DE	No DE
Tie-2	The TEK receptor tyrosine kinase	No DE	No DE	No DE	No DE	No DE	No DE
Vegfa	Vascular endothelial growth factor, a	-1.02	-1.01	-1.05	-1.04	No DE	No DE
Vegfb	Vascular endothelial growth factor, b	-1.37	-1.02	-1.84	-1.11	No DE	No DE
Vegfc	Vascular endothelial growth factor, c	No DE	No DE	No DE	No DE	No DE	No DE
Vegfd	Vascular endothelial growth factor, d	1.76	1.07	1.39	1.27	No DE	No DE