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. 2011 May 27;39(16):7249–7262. doi: 10.1093/nar/gkr423

Figure 5.

Figure 5.

Suppression of neurodegeneration at 30 days in Adar5G1 mutant flies by human ADAR2. (A and B): Haematoxylin and eosin stained frontal sections of 30-day-old Adar5G1; Cha-GAL4, UAS-ADAR1p110 heads show rescue of neurodegeneration in the mushroom body (MB) calyces of the Adar5G1 mutant. (A). Some small vacuoles remain in the retina (B). Arrows indicate vacuolization. (C and D): Frontal sections of 30-day-old Adar5G1; Cha-GAL4, UAS-ADAR1p150 heads show lack of neurodegeneration rescue in the MB calyces of Adar5G1 (C) The retina degenerated rapidly (D). (E and F): Frontal sections of 30-day-old Adar5G1; Cha-GAL4, UAS-ADAR2 heads show rescue of vacuolization of the MB calyces (E) and the eye (F). Scale bars: 20 µM.