Table 3.
Heritability of total and free testosterone and SHBG in adult women from the FHS Generations 2 and 3: bivariate analysis
| Total testosterone and SHBG | Total testosterone and free testosterone | SHBG and free testosterone | |
|---|---|---|---|
| n | 2677 | 2671 | 2677 |
| ρG (se) | 0.31 (0.10) | 0.54 (0.09) | −0.60 (0.08) |
| P value | |||
| Ho: ρG = 0 | 3.32 × 10−3 | 1.69 × 10−3 | 1.93 × 10−8 |
| Ho: ρG = 1 | 3.00 × 10−7 | 1.54 × 10−9 | 1.29 × 10−5 |
| ρE (se) | 0.10 (0.06) | 0.85 (0.017) | −0.37 (0.053) |
| P value | |||
| Ho: ρE = 0 | 0.14 | 2.23 × 10−8 | 9.78 × 10−44 |
| ρP | 0.171 | 0.769 | −0.440 |
Covariates included age, age2, BMI, BMI2, menopausal status, diabetes, and current smoking. ρE, Environmental correlation; ρG, genetic correlation; ρP = phenotypic correlation; Ho, null hypothesis.