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6 weeks after S. japonicum challenge, the livers of mice immunized with PBS (control), vector, rSj23LHD-GST, nirB strain, nirB prime-boost or vector prime-boost were collected, fixed and sectioned for hematoxylin-eosin (H&E) staining. (A) Representative granuloma was shown (magnification, ×400) and (B) granuloma area was measured, Mean ± SD, n = 12–15. *P<0.05, and ***P<0.001.
