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. 2011 Sep 6;6(9):e24097. doi: 10.1371/journal.pone.0024097

Figure 2. Temporal characterisation of P2X7 – NLRP3 inflammasome associated end points in the CS driven murine model.

Figure 2

Mice were challenged with air or CS (1 hour, twice a day, for 3 days) and samples collected at various times after the last challenge. (A) Caspase 1 activity in the lung tissue (B) IL-1β levels in the BALF (C) IL-18 levels in the BALF (D) numbers of neutrophils in the BALF. Data represent mean ± s.e.mean, n = 6. * indicates statistically significant difference from time matched control group (Mann-Whitney test).