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. 2011 Sep 6;6(9):e24097. doi: 10.1371/journal.pone.0024097

Figure 4. Role of the P2X7 – NLRP3 inflammasome axis in the CS driven murine model.

Figure 4

Wild type or P2X7 knockout mice were challenged with air or CS and samples collected 24 hours after the last challenge. (A) Caspase 1 activity in the lung tissue (B) IL-1β levels in the BALF (C) IL-1α levels in the BALF (D) IL-6 levels in the BALF (E) KC levels in the BALF (F) numbers of neutrophils in the BALF. Data represent mean ± s.e.mean, n = 8. # indicates statistically significant difference from air challenge control group. * indicates statistically significant difference from CS challenged control group (Mann-Whitney test).