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Distribution of bacteria in BALB/c mice challenged with exponential-phase cells (a) or biofilm-phase cells (b) of the wild-type strain C50041 and the spiA mutant ΔspiA. Six-week-old BALB/c mice were intraperitoneally injected with 0.2 ml of bacterial suspension. The numbers of bacteria present in the blood, liver, spleen and lungs of the mice were measured 6 and 48 h post-challenge. Significant differences in the bacterial counts of organs were determined by Student’s t-test. *, P<0.05.
