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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Gene. 2011 Jul 19;487(1):21–28. doi: 10.1016/j.gene.2011.07.004

Table 2.

Gene functional categories significantly enriched in the 345 IRF1 targets

Term Count P Value* Genes
PIRSF001733: tripartite motif-containing protein 7 1.99E-07 TRIM5, TRIM34, TRIM50, TRIM26, TRIM21, TRIM74, TRIM73
GO: 0019882~antigen processing and presentation 11 1.21E-06 HLA-H, PSME1, TAP2, CD209, ERAP1, ERAP2, TAPBPL, PSMB8, TAPBP, PSMB9, B2M
IPR007904: APOBEC-like, C-terminal 5 1.45E-05 APOBEC3B, APOBEC3G, APOBEC3F, APOBEC3C, APOBEC3D
GO: 0006955~immune response 28 3.64E-05 OAS3, TLR3, APOBEC3G, IL15, APOBEC3F, IFI35, B2M, TAPBP, FCGR1C, TAP2, TAP1, ERAP1, ERAP2, DHX58, HLA-H, BST2, IL29, TNFRSF14, PSMB8, PSMB9, IL18BP, APOL1, TNFSF13B, PSEN1, ETS1, CD209, CD274, GBP1
IPR012317: Poly(ADP-ribose) polymerase, catalytic region 5 1.50E-04 PARP9, PARP14, PARP3, PARP10, PARP4
IPR008405: Apolipoprotein L 4 1.51E-04 APOL2, APOL1, APOL6, APOL4
Host-virus interaction 15 1.89E-04 HAVCR1, CCNT1, TNFRSF14, APOBEC3G, SP110, APOBEC3F, PSMB8, APOBEC3C, PSMB9, TRIM5, ISG15, TAP2, CD209, TAP1, RBCK1
*

The p values represent the significance of gene enrichment using all known human genes as background.