Table 3.
Association of the 2′‐5′ Oligoadenylate Synthetase 1 Reference Single Nucleotide Polymorphism rs1131454 With Prostate Cancer: Genotype Distribution for All Samples, Caucasian Samples, and African American Samples With Corresponding Odds Ratios, 95% Confidence Intervals, and P Values
| No. (%) | ||||||
|---|---|---|---|---|---|---|
| Genotype | All Samples | Cancer Samples | Normal Samples | OR | 95% CI | P |
| All samples | ||||||
| AA | 56 (18.4) | 24 (14.6) | 32 (22.8) | 0.5786 | 0.322‐1.03 | .0754 |
| AG | 124 (40.7) | 74 (45.1) | 50 (35.7) | 1.4 | 0.931‐2.35 | .102 |
| GG | 124 (40.7) | 66 (40.2) | 58 (41.4) | 0.952 | 0.601‐1.507 | .906 |
| Total | 304 (100) | 164 (100) | 140 (100) | |||
| Caucasian samples | ||||||
| AA | 46 (28.3) | 22 (26.1) | 24 (30.7) | 0.798 | 0.402‐1.582 | .601 |
| AG | 74 (45.6) | 42 (50) | 32 (41) | 1.438 | 0.771‐2.67 | .272 |
| GG | 42 (25.9) | 20 (23.8) | 22 (28.2) | 0.795 | 0.393‐1.608 | .591 |
| Total | 162 (100) | 84 (100) | 78 (100) | |||
| African American samples | ||||||
| AA | 10 (7) | 2 (2.5) | 8 (12.9) | 0.173 | 0.0353‐0.847 | .02 |
| AG | 50 (35.2) | 32 (40) | 18 (29) | 1.63 | 0.802‐3.3 | .215 |
| GG | 82 (57.7) | 46 (57.5) | 36 (58) | 0.977 | 0.499‐1.913 | 1 |
| Total | 142 (100) | 80 (100) | 62 (100) | |||
Abbreviations: AA, adenine‐adenine genotype; AG, adenine‐guanine genotype; CI, confidence interval; GG, guanine‐guanine genotype; OR, odds ratio.