Table 4.
Association of the 2′‐5′ Oligoadenylate Synthetase 1 Reference Single Nucleotide Polymorphism rs34137742 With Prostate Cancer: Genotype Distribution for All Samples, Caucasian Samples, and African American Samples With Corresponding Odds Ratios, 95% Confidence Intervals, and P Values
| No. (%) | ||||||
|---|---|---|---|---|---|---|
| Genotype | All Samples | Cancer Samples | Normal Samples | OR | 95% CI | P |
| All samples | ||||||
| CC | 202 (66.4) | 104 (63.4) | 98 (70) | 0.742 | 0.459‐1.202 | .272 |
| CT | 86 (28.2) | 52 (31.7) | 34 (24.2) | 1.447 | 0.871‐2.4 | .162 |
| TT | 16 (5.2) | 8 (4.8) | 8 (5.7) | 0.846 | 0.309‐2.317 | .8004 |
| Total | 304 (100) | 164 (100) | 140 (100) | |||
| Caucasian samples | ||||||
| CC | 144 (88.8) | 72 (85.7) | 72 (92.3) | 0.5 | 0.1777‐1.405 | .216 |
| CT | 16 (9.8) | 10 (11.9) | 6 (7.6) | 1.622 | 0.560‐4.69 | .436 |
| TT | 2 (1.2) | 2 (2.3) | 0 (0) | 4.758 | 0.224 ‐100.7 | .496 |
| Total | 162 (100) | 84 1(00) | 78 (100) | |||
| African American samples | ||||||
| CC | 58 (40.8) | 32 (40) | 26 (41.9) | 0.923 | 0.470‐1.812 | .864 |
| CT | 70 (49.2) | 42 (52.5) | 28 (45.1) | 1.342 | 0.689‐2.611 | .402 |
| TT | 14 (9.8) | 6 (7.5) | 8 (12.9) | 0.547 | 0.179‐1.670 | .395 |
| Total | 142 (100) | 80 (100) | 62 (100) | |||
Abbreviations: CC, cytosine‐cytosine genotype; CI, confidence interval; CT, cytosine‐thymine genotype; OR, odds ratio; TT, thymine‐thymine genotype.