Table 1.
SNPs genotyped in the VDR gene and their chromosomal position (chromosome 12 genomic contig, NT_029419.11) and allelic frequencies in the samples from the HapMap populations, the total Brazilian population and the five geopolitical regional samples.
| SNP (locus) | Position | Allele | CEU | YRI | ASN | BRZ | N | NE | MW | SE | S |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4077869 | 46591911 | A | N.A. | 0.400 | 0.978 | 0.667 | 0.538 | 0.650 | 0.650 | 0.731 | 0.769 |
| rs11568820 (Cdx2) | 46588812 | C | 0.792 | 0.017 | 0.506 | 0.684 | 0.663 | 0.705 | 0.637 | 0.688 | 0.731 |
| rs4516035 | 46586093 | A | 0.575 | 0.992 | 0.989 | 0.788 | 0.778 | 0.786 | 0.789 | 0.684 | 0.958 |
| rs10783219 | 46581755 | A | 0.331 | 0.000 | 0.416 | 0.306 | 0.244 | 0.325 | 0.333 | 0.282 | 0.346 |
| rs7302235 | 46579105 | A | 0.741 | 0.425 | N.A. | 0.703 | 0.637 | 0.776 | 0.724 | 0.643 | 0.731 |
| rs3890734 | 46575622 | C | 0.675 | 0.877 | 0.994 | 0.684 | 0.679 | 0.688 | 0.700 | 0.675 | 0.676 |
| rs2853559 | 46569072 | A | 0.424 | 0.169 | 0.421 | 0.449 | 0.414 | 0.544 | 0.545 | 0.395 | 0.361 |
| rs2853564 | 46564754 | A | 0.583 | 0.908 | 0.579 | 0.372 | 0.262 | 0.338 | 0.410 | 0.488 | 0.363 |
| rs2254210 | 46559981 | C | 0.633 | 0.658 | 0.624 | 0.688 | 0.700 | 0.712 | 0.675 | 0.613 | 0.738 |
| rs10735810 (FokI) | 46559162 | C | 0.525 | 0.833 | 0.646 | 0.674 | 0.675 | 0.744 | 0.667 | 0.628 | 0.658 |
| rs886441 | 46549231 | A | 0.808 | 0.583 | 0.978 | 0.767 | 0.800 | 0.718 | 0.868 | 0.705 | 0.744 |
| rs2239179 | 46544033 | C | 0.417 | 0.292 | 0.247 | 0.443 | 0.462 | 0.408 | 0.500 | 0.463 | 0.371 |
| rs2248098 | 46539623 | A | 0.425 | 0.381 | 0.663 | 0.465 | 0.387 | 0.551 | 0.425 | 0.450 | 0.512 |
| rs2239185 | 46530826 | A | N.A. | 0.542 | 0.347 | 0.568 | 0.552 | 0.574 | 0.600 | 0.615 | 0.500 |
| rs1544410 (BsmI) | 46526102 | C | 0.525 | 0.712 | 0.921 | 0.605 | 0.637 | 0.590 | 0.618 | 0.526 | 0.654 |
| rs7975232 (ApaI) | 46525104 | G | 0.424 | 0.375 | 0.645 | 0.460 | 0.475 | 0.500 | 0.425 | 0.385 | 0.512 |
| rs731236 (TaqI) | 46525024 | A | 0.526 | 0.750 | 0.933 | 0.627 | 0.625 | 0.603 | 0.700 | 0.551 | 0.654 |
| rs9729 | 46522890 | G | 0.414 | 0.337 | 0.657 | 0.390 | 0.375 | 0.395 | 0.412 | 0.295 | 0.474 |
| rs7968585 | 46518360 | A | 0.592 | 0.633 | 0.326 | 0.525 | 0.500 | 0.483 | 0.433 | 0.645 | 0.528 |
| rs11608702 | 46515035 | A | 0.358 | 0.183 | 0.618 | 0.347 | 0.275 | 0.350 | 0.395 | 0.295 | 0.423 |
| rs2544040 | 46509213 | C | 1.000 | 0.885 | 1.000 | 0.985 | 1.000 | 1.000 | 1.000 | 1.000 | 0.925 |
HapMap populations: CEU = European ancestry, YRI = African ancestry, ASN = Asian ancestry; Total Brazilian population (BRZ) and regional Brazilian samples: N = North, NE = Northeast, MW = Midwest, SE = Southeast, S = South. N.A. = Data not available.