Table 3.
Distribution of the 5′ haplotype frequencies among different populations and the association between Brazilian populations and European ancestry.
| Haplotype frequency
|
Haplotype-specific test (BRZ)
|
||||||
|---|---|---|---|---|---|---|---|
| HAP ID | 5′ HAP | YRI | ASN | CEU | BRZ | EUR-ancestry
|
|
| B | p | ||||||
| 5′H01 | CTT | 0.017 | − | 0.325 | 0.314 | 0.048 | 0.036 * |
| 5′H02 | TTC | 0.883 | 0.494 | 0.208 | 0.309 | − 0.059 | 0.013 * |
| 5′H03 | CAC | − | 0.410 | 0.342 | 0.292 | 0.020 | 0.395 |
| 5′H04 | CTC | − | 0.090 | 0.125 | 0.086 | − 0.039 | 0.281 |
| 5′H05 | TTT | 0.100 | − | − | − | − | − |
HAP ID = Haplotype identity; 5′ HAP = Haplotypes in the 5′ gene region consisting of Cdx2, rs10783219 and rs3890734 SNPs. HapMap populations: ASN = Asian derived ancestry, CEU = European derived ancestry, YRI = African derived ancestry; BRZ = total Brazilian population. EUR = European genetic ancestry. B = raw regression coefficient. p < 0.05 indicates a significant correlation.