Table 5.
Distribution of the Bsm-Apa-Taq haplotype frequencies among different populations and the association between Brazilian populations and European (EUR) and Amerindian (AMR) ancestry.
| Bsm-Apa-Taq | Haplotype frequency | Haplotype-specific test (BRZ) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HAP ID | HAP | YRI | ASN | CEU | BRZ | AMR-ancestry
|
EUR-ancestry
|
||
| B | p | B | p | ||||||
| baT | CGA | 0.367 | 0.657 | 0.417 | 0.418 | 0.013 | 0.279 | − 0.006 | 0.766 |
| BAt | TTG | 0.158 | 0.062 | 0.475 | 0.332 | − 0.044 | 0.001* | 0.058 | 0.008* |
| bAT | CTA | 0.258 | 0.258 | 0.108 | 0.175 | 0.037 | 0.005* | − 0.065 | 0.007* |
| Bat | TGG | − | − | − | 0.023 | − 0.090 | 0.189 | 0.071 | 0.422 |
| BAT | TTA | 0.125 | 0.017 | − | 0.022 | − 0.008 | 0.858 | − 0.089 | 0.155 |
| BaT | TGA | − | − | − | 0.017 | − 0.022 | 0.760 | − 0.022 | 0.800 |
| bAt | CTG | 0.083 | − | − | 0.013 | − 0.073 | 0.286 | 0.121 | 0.242 |
HAP ID = Haplotype identity; HAP = Haplotypes in the gene region consisting of BsmI, ApaI and TaqI SNPs. HapMap populations: ASN = Asian derived ancestry, CEU = European derived ancestry, YRI = African derived ancestry; BRZ = total Brazilian population. AMR = Amerindian genetic ancestry; EUR = European genetic ancestry. B = raw regression coefficient.
*
(p < 0.05) indicates a significant correlation.