Figure 1.

 Phenotypes of strains carrying mutations in pap1⁺, sty1⁺, or atf1⁺. pap1⁻ and sty1⁻ cells were hypersensitive to a variety of cytotoxic compounds. Approximately 10³ cells from exponentially growing cultures of each strain were spotted onto YE5S plates containing the indicated compounds: t-BOOH (0.5 mm); diamide (2 mm); cadmium sulfate (0.1 mm); sodium arsenite (0.5 mm); cisplatin (0.5 mm); cycloheximide (15 μg/ml); staurosporine (0.5 μg/ml); anisomycin (7.5 μg/ml). Plates were incubated at 30°C for 2–3 days.