Table 1.
Baseline demographics by diagnostic category.
| GHD | MPHD | Turner | SGA | ISS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | n | Mean (SD) | |
| Gender | ||||||||||
| Male | 543 | - | 53 | - | 0 | - | 33 | - | 91 | - |
| Female | 155 | - | 18 | - | 60 | - | 17 | - | 32 | - |
| Age | 698 | 10.9 (3.46) | 71 | 6.4 (5.23) | 60 | 8.5 (4.17) | 50 | 7.1 (3.41) | 123 | 11.2 (2.88) |
| HSDS | 698 | -2.2 (0.86) | 71 | -2.0 (1.36) | 60 | -2.5 (0.77) | 50 | -2.8 (0.97) | 123 | -2.3 (0.68) |
| IGF-I SDS | 605 | -2.5 (1.26) | 31 | -3.2 (1.54) | 34 | -2.0 (1.43) | 32 | -2.1 (1.53) | 114 | -2.2 (1.11) |
| BMI SDS | 681 | -0.1 (1.38) | 49 | 0.5 (1.84) | 55 | 0.5 (0.97) | 49 | -0.8 (1.35) | 123 | -0.8 (3.38) |
| Bone Age, yrs | 616 | 9.4 (3.31) | 39 | 8.0 (4.58) | 43 | 7.8 (3.45) | 44 | 6.1 (3.36) | 115 | 9.7 (2.93) |
| Peak GH, ng/mL | 606 | 5.5 (2.69) | 40 | 3.6 (3.03) | 5 | 12.5 (8.25) | 17 | 13.8 (10.95) | 97 | 15.2 (8.10) |
| GH dose, μg/kg/day | 697 | 45.9 (10.1) | 71 | 40.6 (11.2) | 60 | 51.9 (9.0) | 50 | 49.9 (13.5) | 123 | 46.1 (8.6) |
BMI, body mass index; GH, growth hormone; GHD, growth hormone deficiency; HSDS, height standard deviation score; IGF-I, insulin-like growth factor I; ISS, idiopathic short stature; MPHD, multiple pituitary hormone deficiency; SD, standard deviation; SDS, standard deviation score; SGA, small for gestational age