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. 2011 Sep 7;6(9):e23898. doi: 10.1371/journal.pone.0023898

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Cavaliere, Hodge.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Representative traces showing dKCNQ (A) current (black) was sensitive to block by 10 µM XE991 (grey), this is also reflected in the downward shift of the I-V curve (C). Traces (B) and I-V curves (D) showing KCNQ2/3 was sensitive to block by 10 µM XE991. The block was reversible. (E) Dose response curve for XE991 effect on dKCNQ current. dKCNQ n = 6 and KCNQ2/KCNQ3 n = 6.