Figure 5. CB2 agonist inhibits CXCL12-induced focal adhesions and stress fibres formation.
Confocal microscopic visualization of (A) MCF-7/CXCR4 for focal adhesion (stained for Vinculin) or (B) SCP2 cells for stress fibers (stained for phalloidin). The cells were pretreated with vehicle or JWH-015 (20 µm) overnight and then stimulated with CXCL12 (100 ng/ml; 30 min).