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. Author manuscript; available in PMC: 2011 Sep 7.
Published in final edited form as: Bioinformatics. 2008 May 27;24(14):1619–1624. doi: 10.1093/bioinformatics/btn246

Table 1.

Parameter estimates and the standard errors for ODEs (1) and (2) from the measured expressions of Genes Y and Z

Parameters αy αz Kxy Kxz Kyz
FFL 1: X: Gene GCN4; Y: Gene LEU3; Z: Gene ILV5
 Estimates 0.44 0.69 0.90 0.60 0.56
 Standard Errors 0.22 0.18 0.33 0.06 0.15
FFL 2: X: Gene GCN4; Y: Gene LEU3; Z: Gene ILV1
 Estimates 0.44 0.90 0.90 0.75 1.21
 Standard Errors 0.22 0.01 0.33 0.44 0.74
FFL 3: X: Gene PDR1; Y: Gene PDR3; Z: Gene PDR5
 Estimates 0.32 0.56 2.11 1.06 0.76
 Standard Errors 0.15 0.12 0.74 0.32 0.21

Each component is approximated by cubic B-splines with 40 equal spaced knots. The smoothing parameter λ=1000.