Table 5.
Spearman partial correlation between long interspersed nucleotide elements (LINE-1) methylation and selected biomarkersa
| LINE-1 Methylation |
||
|---|---|---|
| Biomarker | Correlation Coefficient | P-valueb |
| Homocysteine | −0.135 | 0.013 |
| Methionine | 0.099 | 0.069 |
| SAM | 0.007 | 0.903 |
| SAH | −0.067 | 0.216 |
| SAM/SAH | 0.048 | 0.381 |
| Folate | 0.057 | 0.294 |
SAM, S-adenosylmethionine; SAH, S-adenosylhomocysteine.
Adjusted for age, race, vitamin supplementation, smoking, alcohol consumption, and body mass index (BMI).