Table 1.
Gene expression changes with >1.2-fold change (P < 0.05) in response to long-term resveratrol (12 months) treatment in middle-aged mice compared to age-matched controls
| Name | Fold change | Regulation | p value | Reference sequence |
|---|---|---|---|---|
| CD72 | 2.02 | ↓ | 0.0221 | NM_007654 |
| NM_007654 | 1.45 | ↓ | 0.0045 | NM_021501 |
| GADD153 | 1.32 | ↓ | 0.0054 | NM_007837 |
| CD79B | 1.30 | ↓ | 0.0388 | NM_008339 |
| IL12RB2 | 1.25 | ↓ | 0.0014 | NM_008354 |
| MBD1 | 1.24 | ↓ | 0.0000 | NM_013594 |
| DNAJC2 | 1.24 | ↓ | 0.0202 | NM_009584 |
| CSF2 | 1.23 | ↓ | 0.0186 | NM_009969 |
| TSGA14 | 1.23 | ↓ | 0.0169 | NM_031998 |
| SOS2 | 1.23 | ↓ | 0.0455 | – |
| TNFC | 1.23 | ↓ | 0.0033 | NM_008518 |
| PTGFR | 1.23 | ↓ | 0.0102 | NM_008966 |
| FLAP | 1.74 | ↑ | 0.0061 | NM_009663 |
| HSF4 | 1.62 | ↑ | 0.0065 | NM_011939 |
| KAI1 | 1.45 | ↑ | 0.0212 | NM_007656 |
| IL1R1 | 1.43 | ↑ | 0.0459 | NM_008362 |
| STAT3 | 1.38 | ↑ | 0.0193 | NM_011486 |
| CCL3 | 1.32 | ↑ | 0.0039 | NM_011337 |
| CBLN1 | 1.32 | ↑ | 0.0483 | NM_019626 |
| C1QA | 1.29 | ↑ | 0.0013 | NM_007572 |
| PRKCB_4 | 1.28 | ↑ | 0.0363 | NM_008855 |
| IFNGR1 | 1.28 | ↑ | 0.0480 | NM_010511 |
| ADCY8 | 1.25 | ↑ | 0.0146 | NM_009623 |
| TCF3 | 1.21 | ↑ | 0.0298 | NM_011548 |
↓ and ↑ arrows indicate downregulation or upregulation of gene expression, respectively