Table 1. Intrinsic membrane properties in dentate gyrus granule neurons in response to Fostriecin and cAMP.
Treatment | Background | RMP (mV) | IR (MΩ) | Threshold (mV) |
---|---|---|---|---|
Control | WT | −86.8±1.1 | 547±61 | −33.6±4.3 |
β4 KO | −86.3±0.9 | 557±60 | −24.4±5.1 | |
| ||||
Fostriecin | WT | −86.1±0.9 | 593±98 | −40.9±1.9 |
β4 KO | −85.0±0.8 | 626±59 | −36.3±2.7 | |
| ||||
Fostriecin+Pax. | WT | −84.2±1.2 | 568±84 | −39.6±3.1 |
β4 KO | −85.4±0.9 | 508±41 | −37.5±1.3 | |
| ||||
cAMP | WT | −83.7±1.0 | 491±76 | −37.8±1.3 |
β4 KO | −85.1±0.9 | 459±57 | −38.7±2.1 | |
| ||||
cAMP+Pax. | WT | −83.2±1.2 | 565±52 | −41.5±0.1 |
β4 KO | −85.1±0.9 | 376±30 | −35.2±3.2 |
Intrinsic membrane properties. Mean ± SE.