Skip to main content
. Author manuscript; available in PMC: 2012 Sep 13.
Published in final edited form as: Biochemistry. 2011 Aug 17;50(36):7765–7773. doi: 10.1021/bi2005784

Fig. 10. Induction of Nrf2- (NQO1) and PPARγ-responsive (FABP4/aP2) endogenous gene expression by 12-NO2-LA.

Fig. 10

MCF7-derived cells stably expressing recombinant PPARγ (MCF7/PPARG1-4′) were exposed to variable concentrations of 12-NO2-LA or vehicle control for 3 hr and harvested 9 hr later (12 hr after the start of 12-NO2-LA exposures) for mRNA quantification by Q-RT-PCR as described in Experimental Procedures. Shown are levels of NQO1 (A) and FABP4/aP2 (B) mRNAs expressed in arbitrary units. Bars represent the means of replicate independent experiments (n=6) ± 1 sem. * P<0.05 and *** P<0.001 (t test).