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. Author manuscript; available in PMC: 2012 Sep 13.
Published in final edited form as: Biochemistry. 2011 Aug 17;50(36):7765–7773. doi: 10.1021/bi2005784

Fig. 7. Absence of cross-talk between ARE/Nrf2- and PPRE/PPARγ-directed transcription in response to treatment with SFN and rosiglitazone (RSG).

Fig. 7

MCF7 cells were co-transfected with PPRE-driven firefly luciferase and ARE-driven Renilla luciferase reporters according to transfection scheme 2 (Experimental Procedures). Following induction with 10 μM SFN or 5 μM RSG and subsequent incubations, fold induction over vehicle (DMSO) control of PPRE/PPARγ-driven (open bars) and ARE/Nrf2-driven (black bars) was determined. Error bars: ± 1 sd (n=3).