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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2011 Sep;58(3):263–271. doi: 10.1097/FJC.0b013e3182239eb7

Figure 5.

Figure 5

S17834 increases endothelial SirT1 protein in lesion-prone aortic endothelial cells in C57BL6 wild type mice fed HFHS diet. Examples are shown of SirT1 staining in control chow-fed, HFHS diet-fed, and S17834-treated, HFHS diet-fed mice. Distinct cellular staining in endothelial cells was observed and specifically scored by observers, and average scores for each mouse are shown in the bar graph inset. The asterisk indicates that S17834 treatment significantly increased scores for staining of SirT1 in endothelial cells (P<0.05, 6 mice per group).