Table 1.

Mean^a (CV) values for single-chemical reactivity (RC₅₀ [mM]), toxicity (EC₅₀ [mg/L]), dose-response curve slope (slope), and curve asymmetry (s) obtained with Microtox

Agent	RC50b	EC50			Slope			s
		15 min	30 min	45 min	15 min	30 min	45 min	15 min	30 min	45 min
EIAC	0.03	0.31 (19.4)	0.13 (23.9)	0.07 (27.9)	1.42 (5.8)	1.85 (7.3)	2.01 (6.5)	0.68 (21.9)	0.36 (21.1)	0.27 (21.0)
EBAC	0.08	1.09 (4.8)	0.42 (7.8)	0.22 (12.9)	1.56 (6.0)	1.81 (7.1)	2.01 (10.1)	0.52 (13.4)	0.33 (5.2)	0.24 (5.7)
ECAC	3.0	87.9 (7.9)	54.3 (4.7)	35.4 (8.3)	0.81 (8.1)	0.93 (8.1)	1.11 (7.7)	1.63 (28.6)	1.06 (28.2)	0.59 (23.5)
EFAC	–c	1174.3 (9.2)	1077.4 (9.2)	1009.9 (9.3)	0.61 (4.0)	0.79 (10.5)	1.00 (17.8)	3.52 (32.9)	1.10 (34.2)	0.64 (34.1)
3M2B	–d	39.8 (15.3)	42.8 (14.8)	45.5 (16.1)	0.80 (8.1)	0.80 (6.1)	0.83 (6.8)	2.33 (47.1)	2.23 (52.2)	1.90 (47.5)

^aEC₅₀, slope and curve asymmetry values are means for six separate tests of each agent alone

^bReactivity as measured with GSH as the model nucleophile; values are the means of two replicate tests

^cNot reactive with GSH at 250 mM

^dNot reactive with GSH