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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Arch Environ Contam Toxicol. 2011 Mar 31;61(4):547–557. doi: 10.1007/s00244-011-9663-1

Table 3.

AQ and IQ quotients for EC50 and slope for each combination tested in Microtox as classified by the sham, SN2 TDT-level, or SN2:NPN mixture groups

Mixture groupa EC50-AQ
Slope-AQ
EC50-IQ
Slope-IQ
A:B 15 min 30 min 45 min 15 min 30 min 45 min 15 min 30 min 45 min 15 min 30 min 45 min
Sham
 EIAC:EIAC 1.00 0.93 0.90 0.94 0.93 1.02 1.04 1.07 1.15 0.69 0.78 0.92
 EBAC:EBAC 1.02 1.05 1.00 0.91 1.02 1.01 1.14 1.31 1.42 0.72 0.89 0.97
 ECAC:ECAC 1.01 1.01 0.98 0.90 0.91 0.92 1.29 1.30 1.32 0.70 0.70 0.71
 EFAC:EFAC 0.94 1.00 1.02 0.70 0.86 1.01 1.31 1.46 1.56 0.61 0.72 0.83
 3M2B:3M2B 0.97 0.98 1.02 1.09 0.95 0.97 1.18 1.22 1.26 0.77 0.70 0.71
Full:full
 EIAC:EBAC 1.02 1.01 1.00 0.92 0.94 0.93 1.10 1.22 1.34 0.70 0.84 0.95
Full:high
 EIAC:ECAC 1.02 1.07 1.07 1.14 0.90 0.91 1.17 1.32 1.41 0.82 0.69 0.74
 EBAC:ECAC 1.07 1.09 1.08 0.84 0.85 0.86 1.26 1.37 1.49 0.64 0.65 0.70
Full:low
 EIAC:EFAC 1.12 1.26 1.54 0.81 0.76 0.92 1.42 1.80 2.28 0.64 0.64 0.76
 EBAC:EFAC 0.86 0.95 1.13 0.70 0.65 0.84 1.06 1.35 1.77 0.58 0.53 0.54
High:low
 ECAC:EFAC 0.82 0.83 0.84 0.69 0.64 0.59 1.06 1.20 1.32 0.57 0.51 0.49
SN2:NPN
 EIAC:3M2B 0.90 0.89 0.86 1.09 0.91 0.81 0.97 1.04 1.03 0.77 0.68 0.63
 EBAC:3M2B 0.91 0.86 0.87 1.14 0.97 0.87 0.98 1.02 1.08 0.83 0.71 0.65
 ECAC:3M2B 0.79 0.78 0.77 0.97 0.95 0.89 0.97 0.96 0.99 0.76 0.71 0.68
 EFAC:3M2B 0.87 0.86 0.88 0.81 0.64 0.55 1.07 1.12 1.18 0.57 0.48 0.40
a

Mixture group includes sham, SN2 agent TDT level (full, high, low TDT [see Table 2]), and SN2:NPN (nonpolar narcotic) categories, see Table 1 for chemical names. Values shown in bold are within the range of 0.90 to 1.10 and are consistent with dose-addition if AQ values or independence if IQ values