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. 2011 Mar 26;139(4):752–763. doi: 10.1378/chest.10-1253

Table 4.

—Independent Predictors of GOLD Stage II+ COPD in Never Smokers: Multivariate Logistic Model

Women ( n = 2,578)
Men (n = 1,311)
Variable OR P Value 95% CI OR P Value 95% CI
Age, y
 40-49 Reference Reference
 50-59 1.37 .311 0.75-2.52 2.71 .023 1.14-6.38
 60-69 4.31 < .001 2.50-7.44 4.88 < .001 2.03-11.70
 70-79 6.15 < .001 3.31-11.44 10.85 < .001 4.32-27.22
 80+ 12.97 < .001 6.56-25.65 29.02 < .001 8.56-98.39
Education, y
 1-y increase 0.94 .005 0.90-0.98 0.99 .700 0.93-1.05
≥ 10 y exposure in high-risk occupation
 Organic dust 1.96 .007 1.20-3.20 2.18 .054 0.99-4.80
 Inorganic dusta 0.72 .617 0.19-2.65
 Gases/vapors 0.65 .506 0.18-2.32 1.54 .270 0.71-3.34
Biomass fuel
 ≥ 10 y cooking 1.03 .899 0.67-1.57 1.39 .514 0.52-3.75
 ≥ 10 y heating 0.81 .386 0.50-1.31 0.55 .255 0.20-1.53
Passive smoking
 Exposed 1.53 .064 0.98-2.41 0.97 .954 0.40-2.40
Childhood hospitalization
 Yes 2.21 .087 0.89-5.47 2.82 .065 0.94-8.51
Comorbidities, diagnosis
 HD/HT/DM 1.13 .499 0.79-1.63 1.28 .433 0.69-2.36
 Asthma 4.62 < .001 3.04-7.02 4.12 < .001 2.06-8.26
 TB 1.47 .323 0.69-3.12 1.65 .464 0.43-6.34
BMI, kg/m2
 BMI < 20 2.56 .002 1.40-4.71 13.39 < .001 3.67-48.84
 ≥ 20 BMI < 25 Reference Reference
 ≥ 25 BMI < 30 0.74 .182 0.48-1.15 1.28 .518 0.61-2.67
 ≥ 30 BMI < 35 0.65 .130 0.37-1.14 2.19 .066 0.95-5.05
 BMI ≥ 35 0.62 .147 0.33-1.18 3.19 .030 1.11-9.11

DM = diabetes mellitus; HD = heart disease; HT = hypertension.

a

This term was excluded from the model for women as there were only 11 women with the exposure, none of whom had GOLD stage II+ COPD, making the OR unestimable.