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. 2011 Aug 30;6(8):e24276. doi: 10.1371/journal.pone.0024276

Figure 4. Diannexin (DA5) improves kidney function after renal IRI.

Figure 4

Urine flow and urine glucose were measured at baseline, and 3 and 8 days after renal IRI. Twenty minutes of renal IRI significantly increased both parameters when compared to sham-operated mice on day 3. On day 8, recovery of renal function was observed. (A) When compared to vehicle-treated mice (ctrl), DA5-treatment reduced glucosuria on day 3. (B) Urine flow was increased on day 3 post-ischemia in vehicle-treated controls, which was normalized by DA5 treatment. Values are means ± SEM. *P<0.05, **P<0.01 vs. sham; # P<0.05, ## P<0.001 vs. DA5 group. n = 5 for sham operated mice and n = 10 for all other groups.