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. 2011 Aug 30;6(8):e24226. doi: 10.1371/journal.pone.0024226

Table 3. Helios expression, FOXP3 demethylation, maturation phenotype and Treg suppressive function.

Patient, linical data % Helios expression % Unmethylated FOXP3 in TSDR Suppressive function, AUC % CD31 expression % CD45RA+ D45RO-expression % CD45RO+ D45RA-expression
CD4+ esponders CD8+ esponders
Male, 57 yrs, alcoholic liver disease 1 wk post Tx 74 66 139 97 12 17 22
3 mths post Tx 57 46 105 0 22 27 21
Female, 59 yrs,Primary biliary cirrhosis 1 wk post Tx 74 42 14 5 8 7 88
3 mths post Tx 64 50 35 39 17 7 82
Healthy donor, male, 25-40 yrs 72 76 204 No data 9 27 65