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. 2000 Sep 1;14(17):2134–2139. doi: 10.1101/gad.820400

Figure 4.

Figure 4

A switch in ventral interneuron fates in Nkx6.1 mutant mice. Chx10 expression in V2 neurons at rostral cervical levels of E10.5 wild-type (A) and Nkx6.1 mutant (B) embryos. En1 expression by V1 neurons at rostral cervical levels of wild-type (C) and Nkx6.1 mutant (D) embryos. Pax2 expression in a set of interneurons that includes V1 neurons (Burrill et al. 1997) at caudal hindbrain levels of wild-type (E) and Nkx6.1 mutant (F) embryos. (G,H) Sim1 expression by V3 neurons in the cervical spinal cord of wild-type (G) and Nkx6.1 mutant (H) embryos. Evx1 expression by V0 neurons at caudal hindbrain levels of wild-type (I) and Nkx6.1 mutant (J) embryos. En1 (red) and Lhx3 (green) expression by separate cell populations in the ventral spinal cord of E11 wild-type (K) and Nkx6.1 mutant (L) embryos. Scale bar shown in B = 60 μm (A–D), 75 μm (E,F), 70 μm (G,J,H,J), or 35μ m (K,L).