Figure 3.
Structural changes in subjects with PSP compared to controls. Panel A shows patterns of grey (shown in red) and white matter (shown in green) volume loss in PSP compared to controls assessed using voxel-based morphometry. Results are shown uncorrected for multiple comparisons at p<0.001 on 3D renders and slices through the basal ganglia and thalamus. Panel B shows regions of reduced fractional anisotropy (shown in red) in PSP subjects compared to controls displayed on the TBSS white matter tract skeleton (shown in green). Results are shown after correction for multiple comparisons at p<0.05. ILF = inferior longitudinal fasciculus; SLF = superior longitudinal fasciculus