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. Author manuscript; available in PMC: 2012 Oct 18.
Published in final edited form as: Acc Chem Res. 2011 Apr 29;44(10):914–924. doi: 10.1021/ar200061q

FIGURE 5.

FIGURE 5

(A, D) Photographs of nude mice transplanted with B16 melanomas before the injection of [Nle4, D-Phe7]-α-MSH- and PEG-AuNCs, respectively. PA images of the melanoma (B, E) before injection and (C, F) at 6 h post-injection of the two types of AuNCs. (G) Increase of PA amplitude in the melanoma tumors after intravenous injection of the AuNCs (n = 4 mice for each group) for different periods of time. (H) The average number (per unit tumor mass) of AuNCs accumulated in the melanomas dissected at 6 h post-injection and then measured by ICP-MS.22