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Miranda is required to localize prospero mRNA. prospero mRNA localizes on the apical side of neuroblasts at interphase (arrow in a) and moves to the basal cortex during mitosis (arrowhead in b). In the absence of Miranda, the RNA is evenly distributed in all neuroblasts (c,d,e). The arrowheads in c and d indicate individual neuroblasts. prospero mRNA is labeled in red, DNA in green.
