1 Pain (Time point equal to or less than three months and closest to eight weeks post‐randomization) |
8 |
1999 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.60 [‐0.84, ‐0.36] |
1.1 Acupuncture vs. waiting list control |
4 |
622 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.03 [‐1.35, ‐0.71] |
1.2 Acupuncture vs. supervised osteoarthritis education |
1 |
294 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.51 [‐0.74, ‐0.27] |
1.3 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
218 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.12 [‐0.38, 0.15] |
1.4 Acupuncture vs. home exercises/advice leaflet alone |
1 |
121 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.18 [‐0.54, 0.18] |
1.5 Acupuncture vs. supervised exercise alone |
1 |
120 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.13 [‐0.49, 0.23] |
1.6 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
624 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.60 [‐0.76, ‐0.44] |
2 Function (Time point equal to or less than three months and closest to eight weeks post‐randomization) |
7 |
1973 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.58 [‐0.87, ‐0.30] |
2.1 Acupuncture vs. waiting list control |
3 |
597 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.08 [‐1.48, ‐0.67] |
2.2 Acupuncture vs. supervised osteoarthritis education |
1 |
294 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.52 [‐0.75, ‐0.28] |
2.3 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
218 |
Std. Mean Difference (IV, Random, 95% CI) |
0.00 [‐0.26, 0.27] |
2.4 Acupuncture vs. home exercises/advice leaflet alone |
1 |
121 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.21 [‐0.56, 0.15] |
2.5 Acupuncture vs. supervised exercise alone |
1 |
120 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.05 [‐0.41, 0.31] |
2.6 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
623 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.67 [‐0.83, ‐0.50] |
3 Total score (Time point equal to or less than three months and closest to eight weeks post‐randomization) |
7 |
1969 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.58 [‐0.85, ‐0.30] |
3.1 Acupuncture vs. waiting list control |
3 |
593 |
Std. Mean Difference (IV, Random, 95% CI) |
‐1.08 [‐1.49, ‐0.68] |
3.2 Acupuncture vs. supervised osteoarthritis education |
1 |
294 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.53 [‐0.77, ‐0.30] |
3.3 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
218 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.03 [‐0.30, 0.24] |
3.4 Acupuncture vs. home exercises/advice leaflet alone |
1 |
121 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.21 [‐0.57, 0.15] |
3.5 Acupuncture vs. supervised exercise alone |
1 |
120 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.07 [‐0.43, 0.28] |
3.6 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
623 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.57 [‐0.73, ‐0.41] |
4 Pain (26 weeks after baseline) |
3 |
1088 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.34 [‐0.70, 0.01] |
4.1 Acupuncture vs. supervised osteoarthritis education |
1 |
250 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.54 [‐0.80, ‐0.29] |
4.2 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
213 |
Std. Mean Difference (IV, Random, 95% CI) |
0.06 [‐0.20, 0.33] |
4.3 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
625 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.52 [‐0.68, ‐0.36] |
5 Function (26 weeks after baseline) |
3 |
1093 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.34 [‐0.64, ‐0.04] |
5.1 Acupuncture vs. supervised osteoarthritis education |
1 |
250 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.50 [‐0.75, ‐0.24] |
5.2 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
218 |
Std. Mean Difference (IV, Random, 95% CI) |
0.00 [‐0.26, 0.27] |
5.3 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
625 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.50 [‐0.66, ‐0.34] |
6 Total score (26 weeks after baseline) |
3 |
1084 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.34 [‐0.67, ‐0.01] |
6.1 Acupuncture vs. supervised osteoarthritis education |
1 |
250 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.51 [‐0.77, ‐0.26] |
6.2 Acupuncture as an adjunct to exercise based physiotherapy program (including supervised plus home exercises) vs exercise based physiotherapy program alone (no adjuvant acupuncture) |
1 |
209 |
Std. Mean Difference (IV, Random, 95% CI) |
0.04 [‐0.23, 0.31] |
6.3 Acupuncture vs. physician consultations (with a physiotherapy co‐intervention) |
1 |
625 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.51 [‐0.67, ‐0.35] |