Table 2.

Cycloisomerization reaction of nitrogen- and oxygen-linked 1,6-enynes.

Entry	Enyne		t [h]	Yield [%]a	Product		ee [%]b
1c		1c	17	8		3c	77
2c,d		1c	17	8		3c	89
3c		1d	24	7		3d	35
4c		1e	16	61		3e	13
5c		1b	16	23		3b	22
6		2b	3.5	54		4b	93 (+)
7		2c	15	25		4c	94 (−)
8d		2c	15	64		4c	94 (−)
9		2d	15	32		4d	96 (−)
10d		2d	15	63		4d	98 (−)
11		2e	30	59		4e	95 (−)
12		2f	1	37		4f	95 (−)

^aIsolated yield, ^bdetermined by HPLC, ^c60 °C, ^dAgNTf₂.