Table 2.
Dosimetric and radiobiological indices for 186Re/188Re-liposomes delivering 50 Gy at respective treatment distances.
Index | 186Re | 188Re |
---|---|---|
Injected activity | 30.3 mCi | 50.9 mCi |
HBVa | 998.56 cc | 995.81 cc |
TVb | 0.91 cc | 3.66 cc |
EUD | 58.2 Gy | 72.5 Gy |
EUDhb | 0.23 Gy | 0.39 Gy |
TCP | 0.9999 | 1 |
NTCP | 0.046% | 0.046% |
Avg. dosetv | 1596.1 Gy | 1338.7 Gy |
Avg. dosebreast | 0.12 Gy | 0.23 Gy |
Therapeutic range | 2 mm | 5 mm |
Therapeutic range dose | 50 Gy | 50 Gy |
Dose 1 cm from therapeutic range | 0.56 Gy | 0.61 Gy |
HBV = healthy breast volume.
TV = treatment volume.