Table 1.
Characteristics at baseline among participants in the ARIC Study, by case status
| Control (n = 143) | Case (n = 143) | p value | |
|---|---|---|---|
| Age, yearsa | 64.6 (5.7) | 64.7 (5.5) | − |
| Female, %a | 53.8 | 53.8 | − |
| Black, %a | 22.4 | 22.4 | − |
| Diabetes, % | 14.7 | 18.2 | 0.43 |
| Systolic blood pressure, mm Hg | 127.7(18.1) | 134.2 (19.6) | 0.003 |
| Hypertension medication use, % | 37.1 | 39.9 | 0.63 |
| BMI | 27.6 (4.7) | 29.1 (5.4) | 0.02 |
| Current smoking, % | 14.0 | 12.7 | 0.75 |
| High-density lipoprotein cholesterol, mg/dl | 51.6(18.3) | 49.9 (18.0) | 0.43 |
| Triglycerides, mg/dl | 130.5 (68.5) | 153.1 (91.5) | 0.02 |
| Urinary ACR, mg/g | 3.1 [16.6,6.7] | 3.4 [1.3, 7.7] | 0.62 |
| TFF3, μg/ml | 0.5 [0.2,1.0] | 0.7 [0.4, 1.2] | 0.005 |
| Baseline eGFR, ml/min/1.73 m2 | 83.2 (15.7) | 81.6(14.0) | 0.36 |
| Follow-up eGFR, ml/min/1.73 m2 | 80.8(19.3) | 48.4 (7.6) | − |
| Change in eGFR, ml/min/1.73 m2 | −2.4(18.4) | -33.2 (14.9) | − |
Continuous characteristics are presented as mean (SD) except urinary ACR and TFF3, which are presented as median [25th, 75th percentile].
a
Matching characteristics.