Table 2.
Characteristics of participants in the ARIC Study, by TFF3 quartile
| TFF3, μg/ml |
p trend | ||||
|---|---|---|---|---|---|
| <0.20 | 0.20−0.50 | 0.51−0.96 | ≥0.97 | ||
| Age, years | 65.1 (5.4) | 64.3 (6.0) | 65.5 (5.4) | 63.9 (5.5) | 0.41 |
| Female, % | 75.9 | 45.6 | 46.8 | 51.9 | 0.02 |
| Black, % | 10.3 | 13.2 | 34.2 | 27.2 | 0.002 |
| Systolic blood pressure, mm Hg | 125.8 (15.6) | 131.6 (21.0) | 134.8 (20.6) | 130.3 (17.7) | 0.16 |
| Antihypertensive medication use, % | 29.3 | 33.8 | 39.2 | 48.1 | 0.02 |
| Diabetes, % | 5.2 | 16.2 | 13.9 | 27.2 | 0.002 |
| BMI | 28.4 (6.1) | 29.2 (5.3) | 27.5 (4.5) | 28.3 (4.8) | 0.46 |
| Current smoking, % | 13.8 | 7.4 | 12.7 | 18.8 | 0.21 |
| High-density lipoprotein cholesterol, mg/dl | 53.0 (22.4) | 47.0 (14.6) | 53.3 (9.9) | 49.7(15.2) | 0.79 |
| Triglycerides, mg/dl | 138.9 (69.9) | 146.3 (71.4) | 132.6 (98.7) | 148.9 (78.9) | 0.69 |
| Urinary ACR, mg/g | 4.0 [2.7,7.5] | 2.4 [1.3, 6.4] | 3.1 [1.1,7.4] | 3.5 [1.2,7.1] | 0.15 |
| Baseline eGFR, ml/min/1.73 m2 | 79.2 (11.5) | 84.3 (17.4) | 82.1 (13.3) | 83.5 (14.9) | 0.23 |
| Follow-up eGFR, ml/min/1.73 m2 | 68.5 (18.7) | 64.8 (19.2) | 63.3 (21.7) | 62.9 (25.9) | 0.13 |
| Change in eGFR, ml/min/1.73 m2 | −10.7(19.9) | −19.5(21.2) | −18.8 (22.9) | −20.6 (25.7) | 0.03 |
Continuous characteristics are presented as mean (SD) except urinary ACR, which is presented as median [25th, 75th percentile].