Table 1. SSGCID success rates by taxon.
Taxon | Cloned | Soluble (%) | Purified (%) | Crystals (%) | Diffraction (%) | Structure (%) | Overall (%) |
---|---|---|---|---|---|---|---|
Bacteria | 3383 | 57 | 60 | 51 | 51 | 66 | 6 |
Anaplasma | 162 | 51 | 72 | 29 | 53 | 100 | 6 |
Bartonella | 222 | 64 | 68 | 46 | 71 | 66 | 9 |
Borrelia | 161 | 48 | 61 | 49 | 39 | 56 | 3 |
Brucella | 303 | 61 | 51 | 72 | 64 | 72 | 10 |
Burkholderia | 780 | 54 | 38† | 48 | 70 | 69 | 5† |
Ehrlichia | 120 | 72 | 64 | 44 | 58 | 64 | 8 |
Mycobacterium | 1503 | 59 | 69 | 53 | 41 | 65 | 6 |
Rickettsia | 104 | 47 | 69 | 47 | 50 | 50 | 4 |
Other genera‡ | 28 | 50 | 93 | 38 | 80 | 25 | 4 |
Eukaryotes | 758 | 56 | 71 | 44 | 43 | 61 | 5 |
Babesia | 28 | 61 | 82 | 71 | 60 | 83 | 18 |
Coccidioides | 65 | 57 | 84 | 52 | 56 | 78 | 11 |
Cryptosporidium | 75 | 55 | 68 | 32 | 33 | 33 | 1 |
Encephalitozoon | 116 | 66 | 68 | 48 | 28 | 71 | 4 |
Entamoeba | 245 | 49 | 70 | 39 | 58 | 53 | 4 |
Giardia | 116 | 59 | 88 | 45 | 33 | 56 | 4 |
Toxoplasma | 81 | 60 | 49 | 42 | 30 | 33 | 1 |
Other genera§ | 32 | 41 | 62 | 38 | 33 | 100 | 3 |
Viruses | 30 | 47 | 93 | 69 | 44 | 75 | 11 |
Filoviridae § | 5 | 20 | 0 | 0 | |||
Orthomyxoviridae | 25 | 52 | 100 | 69 | 44 | 75 | 12 |
Other viruses | 7 | 43 | 67 | 50 | 100 | 100 | 14 |
Total | 4178 | 57 | 62 | 50 | 50 | 66 | 6 |
The success rate for Burkholderia is artificially low, since purification of a large number of soluble targets has not yet been completed.
Bacterial and eukaryotic genera with 25 or fewer targets are not shown individually.
Viruses are grouped by family.