Table 1.
Clinical and demographic data of the study population used for ex vivo gene expression analysis (age, sex, diagnosis, Thompson grade [29], vertebral level)
| Sample | Sex | Age | Diagnosis | Grade | Level | Region |
|---|---|---|---|---|---|---|
| 1 | M | 31 | DDD | II | L5/S1 | NP |
| 2a | F | 39 | Trauma | II | C4/5 | AF |
| 2b | F | 39 | Trauma | II | C4/5 | NP |
| 3a | F | 57 | Trauma | II | Th10/11 | AF |
| 3b | F | 57 | Trauma | II | Th10/11 | NP |
| 4a | F | 70 | Trauma | II | Th12/L1 | AF |
| 4b | F | 70 | Trauma | II | Th12/L1 | NP |
| 5a | M | 29 | Trauma | III | L1/2 | AF |
| 5b | M | 29 | Trauma | III | L1/2 | NP |
| 6a | F | 34 | DDD | III | L4/5 | AF |
| 6b | F | 34 | DDD | III | L4/5 | NP |
| 7a | M | 41 | DDD | III | C4/5 | AF |
| 7b | M | 41 | DDD | III | C4/5 | NP |
| 8 | M | 46 | DDD | III | L5/6 | NP |
| 9a | M | 25 | DDD | IV | L5/S1 | AF |
| 9b | M | 25 | DDD | IV | L5/S1 | NP |
| 10 | M | 44 | DDD | IV | L5/S1 | AF+NP |
| 11 | M | 50 | DDD | IV | L5/S1 | AF+NP |
| 12 | M | 55 | Spondylodesis | IV | C3/4 | AF+NP |
| 13a | F | 58 | Spondylodesis | IV | C5/6 | AF |
| 13b | F | 58 | Spondylodesis | IV | C5/6 | NP |
| 14 | M | 37 | DDD | V | L5/S1 | AF+NP |
| 15a | F | 41 | DDD | V | L3/4 | AF |
| 15b | F | 41 | DDD | V | L3/4 | NP |
| 16a | M | 67 | DDD | V | L5/S1 | AF |
| 16b | M | 67 | DDD | V | L5/S1 | NP |
| 17a | M | 72 | DDD | V | L4/5 | AF |
| 17b | M | 72 | DDD | V | L4/5 | NP |
M = male, F = female, NP = nucleus pulposus, AF = annulus fibrosus. DDD = degenerative disc disease, C = cervical, Th = thoracic, L = lumbar, S = sacral (degeneration grade according to Thompson)