Table 2.
Differentially expressed immune genes between IPNV isolates, as assessed by microarray analyses of head kidney at 13 d p.i.
| Accession | Gene | Isolate NFH-Ar | Isolate NFH-El |
|---|---|---|---|
| Virus responsive | |||
| GE828737 | Beta-2 microglobulin BA1 | 1.46 ± 0.21 | 0.31 ± 0.19 |
| CX026208 | Beta-2-microglobulin JB1 | 1.27 ± 0.24 | 0.37 ± 0.12 |
| CA043257 | MHC class 1b antigen | 0.91 ± 0.17 | 0.16 ± 0.12 |
| CU070775 | MHC class I heavy chain-1 | 0.98 ± 0.19 | 0.21 ± 0.07 |
| BX857730 | Proteasome subunit beta type 9 | 0.62 ± 0.09 | 0.10 ± 0.03 |
| CU071943 | Galectin 9-1 | 0.60 ± 0.17 | -0.06 ± 0.13 |
| CX035552 | Galectin 9-2 | 1.50 ± 0.44 | 0.03 ± 0.11 |
| CA353586 | Galectin 9-3 | 2.33 ± 0.41 | 0.47 ± 0.10 |
| CA379576 | Galectin like 2 | 1.14 ± 0.31 | 0.19 ± 0.12 |
| CA379898 | Galectin like 1 | 1.34 ± 0.39 | -0.24 ± 0.09 |
| BX079375 | Galectin-3 binding protein | 1.83 ± 0.25 | 0.21 ± 0.17 |
| CA367930 | Interferon inducible protein 1 | 0.76 ± 0.17 | 0.58 ± 0.21 |
| CA363130 | Interferon-induced 35 kDa protein | 0.75 ± 0.23 | -0.03 ± 0.06 |
| CA376422 | Interferon-induced protein 44-2 | 0.70 ± 0.16 | 0.17 ± 0.08 |
| CA381440 | Double-stranded RNA-specific adenosine deaminase | 0.70 ± 0.16 | 0.11 ± 0.09 |
| CA378782 | Tyrosine-protein kinase Jak1-2 | 0.99 ± 0.31 | -0.28 ± 0.13 |
| CA373850 | STAT1 | 1.11 ± 0.22 | 0.02 ± 0.11 |
| CA376536 | Tripartite motif (VRG3) | 1.68 ± 0.19 | 0.41 ± 0.12 |
| CA349577 | Tyrosine-protein kinase SRK2 | 1.85 ± 0.57 | -0.32 ± 0.10 |
| Chemokines, cytokines, receptors and transducers | |||
| CA361535 | CC chemokine SCYA106 | 1.64 ± 0.40 | 0.03 ± 0.12 |
| CA366435 | CC chemokine SCYA110-1 | -0.91 ± 0.10 | -0.77 ± 0.08 |
| CA374135 | CCL4 | -0.78 ± 0.09 | -0.78 ± 0.12 |
| CA378286 | Interleukin-1 receptor-associated kinase 1-2 | 0.71 ± 0.15 | 0.78 ± 0.13 |
| CA362179 | Interleukin-1 receptor-like protein 2 | 0.85 ± 0.21 | -0.37 ± 0.12 |
| CA361101 | Regulator of G-protein signaling 1-2 | 0.81 ± 0.18 | 0.52 ± 0.22 |
| CF752495 | Transcription factor jun-B-1 | 0.59 ± 0.13 | -0.18 ± 0.10 |
| CA342573 | TNF receptor superfamily member 11B | 1.48 ± 0.31 | 0.10 ± 0.14 |
| Eicosanoid metabolism | |||
| CA346166 | Arachidonate 5-lipoxygenase-1 | 0.59 ± 0.07 | 0.78 ± 0.14 |
| BX890112 | Cytochrome P450 2F1 | -1.03 ± 0.04 | -0.94 ± 0.11 |
| EV384586 | Cytochrome P450 2K4 | -1.08 ± 0.07 | -1.06 ± 0.19 |
| CA372428 | Leukotriene B4 receptor 1 | -0.98 ± 0.10 | -1.04 ± 0.12 |
| CA366643 | Prostaglandine D synthase | -1.13 ± 0.20 | 0.28 ± 0.21 |
| Complement, lectins, effectors | |||
| CA359451 | C type lectin receptor C | -0.72 ± 0.05 | -0.65 ± 0.17 |
| CA363676 | Complement factor B/C2-B | -0.96 ± 0.08 | -0.88 ± 0.11 |
| BX082584 | Complement factor H-1 | -0.92 ± 0.07 | -0.61 ± 0.12 |
| BX075495 | High affinity Ig Fc receptor I | 0.93 ± 0.29 | 0.20 ± 0.15 |
| CA367288 | Properdin | 1.02 ± 0.16 | 0.89 ± 0.15 |
| CA376803 | Serine protease-like protein-2 | -0.68 ± 0.15 | -0.21 ± 0.15 |
| CR943302 | Tolloid-like protein (nephrosin)-1 | -0.44 ± 0.11 | -1.08 ± 0.30 |
| CA370329 | Lysozyme C precursor | 0.71 ± 0.13 | -0.04 ± 0.09 |
| CA385270 | Granulins | 0.73 ± 0.14 | 0.25 ± 0.02 |
| CF752659 | Ferritin heavy chain-1 | 0.82 ± 0.12 | 0.56 ± 0.24 |
| CA345780 | Lysozyme g-2 | -0.90 ± 0.10 | -0.49 ± 0.36 |
| Apoptosis, cell cycle | |||
| CX720700 | BCL2/adenovirus E1B protein-interacting | 1.49 ± 0.29 | 0.93 ± 0.19 |
| CA366608 | CASP8 and FADD-like apoptosis regulator | 1.09 ± 0.11 | 0.63 ± 0.14 |
| CA384134 | G1/S-specific cyclin D2 | 1.98 ± 0.41 | -0.12 ± 0.31 |
| CA377697 | Platelet-derived endothelial cell growth factor | 0.72 ± 0.15 | 0.47 ± 0.09 |
| CA376673 | Pre-B cell enhancing factor | 1.47 ± 0.34 | 0.28 ± 0.11 |
Data are log2-ER ± SE. Significant difference between the study groups (t-test, p < 0.05) is indicated with italics.