Table 5. Number of observed abnormalities/number of embryos examined at 200 uM injection (kcnq1) and 400 uM injection (dok6 and fndc1).
| Global Renal Marker pax2a | Podocyte Marker wt1a | Podocyte Marker nephrin | Proximal Tubular Marker slc20a1a | Distal Tubular Marker slc12a3 | |
| Control MO | 2/49 (4.1%) | 3/63 (4.8%) | 2/47 (4.3%) | 45/142 (31%) | 0/62 (0%) |
| kcnq1 | |||||
| Splice | 45/68 (66%) | 30/60 (50%) | 35/50 (70%) | 54/143 (38%) | 0/35 (0%) |
| ATG | 46/68 (68%) | 33/78 (42%) | 29/46 (63%) | 65/157 (41%) | 0/41 (0%) |
| Chi-Sqr p-value* | <0.0001 | <0.0001 | <0.0001 | 0.34 | 1 |
| Chi-Sqr p-value** | <0.0001 | <0.0001 | <0.0001 | 0.11 | 1 |
| Uninjected control | 0/38 (0%) | 0/31 (0%) | 0/60 (0%) | 1/16 (6%) | 0/18 (0%) |
| dok6 | |||||
| ATG | 5/54 (9%) | 3/28 (11%) | 1/50 (2%) | 5/32 (16%) | 2/42 (5%) |
| Chi-Sqr p-value** | 0.14 | 0.2 | 0.93 | 0.65 | 0.88 |
| fndc1 | |||||
| Splice | 4/39 (10%) | 1/30 (3%) | 0/51 (0%) | 8/31 (26%) | 0/35 (0%) |
| Chi-Sqr p-value* | 0.13 | 0.99 | 1 | 0.22 | 1 |
*Control or Uninjected versus splice MO.
**Control or Uninjected versus ATG MO.