Table 3. Statistical characterization of 1H NMR mQTL effects.
| Discovery Stage (MolTWIN) | Replication Stage (MolOBB) | ||||||
| ID | Betaa | S.E. Beta | p-value | Beta | S.E. Beta | p-value | Replicatedb |
| TMAu | -1.10 | 0.08 | 2.8E-23 | -1.19 | 0.12 | 7.9E-15 | * |
| N-ACu | 1.06 | 0.09 | 4.1E-19 | 1.10 | 0.13 | 1.4E-11 | * |
| BAIBu | 1.54 | 0.21 | 5.9E-11 | 1.25 | 0.23 | 1.1E-06 | * |
| DMAp | -0.65 | 0.09 | 8.6E-11 | -0.52 | 0.19 | 0.0081 | * |
a
Additive genetic effect with increasing number of copies of the minor allele (minor/major alleles are shown in Table 1).
b
Significant at a level of 0.0125 (significance level of 0.05 adjusted for conducting 4 tests by the Bonferroni method).