Table 1. GRIM-1 expression levels in normal and tumor specimens analyzed by immunohistochemistry.
Level@ → | Normal | Tumor | Loss (%) | ||||||||||
+ | ++ | +++ | ++++ | +++++ | Total | + | ++ | +++ | ++++ | +++++ | Total | ||
Prostate | 4 | 5 | 7 | 14 | 8 | 38 | 21 | 17 | 8 | 46 | |||
Prostate (paired) | 3 | 3 | 4 | 8 | 6 | 24 | 7 | 11 | 6 | 24 | 75 |
@Expression level graded on an arbitrary scale (%) using signal ratio of GRIM-1 to DAPI.
+ (0–20) – Severe loss, ++ (21–40) – Significant loss, +++ (41–60) – Moderate loss, ++++ (61–80) – Slight loss, +++++ (81–100) – No loss.