Skip to main content
. 2011 Sep 8;6(9):e24168. doi: 10.1371/journal.pone.0024168

Figure 6. CG7375 negatively regulates CiFL stability and Hh signaling.

Figure 6

RNAi knockdown of CG7375 in the dorsal compartment of the wing disc (box bracket) led to accumulation of CiFL (A) and expansion of dpp-lacZ (B). Analysis of CG7375 RNAi-overexpressing clones (positively marked by mCD8-GFP in E and H) confirmed that CiFL stability (D, arrowhead) and Col expression (G, arrowhead) were cell-autonomously regulated by CG7375 in the anterior compartment of the wing disc. Similarly, ectopic Col expression (J, arrowheads) was observed in loss-of-function CG7375LL04684 somatic clones (negatively marked by nGFP in K) in the wing disc.