Table 1. Endogenous circadian rhythms in platelet function from cosinor analyses.

Variable	P-value circadian	P-value harmonic	Timing peak (degrees)	Timing peak (clocktime)	Peak-to-trough amplitude	Peak-to-trough amplitude (% of mean)
GPIIb-IIIa	0.012	n.s.	70°	∼9AM	5.1% pos	17%
P-selectin	0.0065	n.s.	70°	∼9AM	0.22 MFI	6%
GPIb	0.0008	n.s.	50°	∼8AM	19.8 MFI	9%
Estimated platelet size	<0.0001	n.s.	30°	∼6:30AM	2.0 A.U.	2%
Aggregability	0.033	n.s.	230°	∼8PM	3.6Ω*min	4%
ATP release	0.023	n.s.	160°	∼3PM	0.08nM	16%
Platelet count	0.0099	n.s.	160°	∼3PM	0.12×105/µL	6%
Epinephrine	<0.0001	0.0087	210°	∼6:30PM	17 pg/mL	68%