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. 2011 Sep 8;6(9):e24611. doi: 10.1371/journal.pone.0024611

Figure 5. Effect of CXXC mutations on uptake and intracellular replication in J774A1.

Figure 5

Monolayers of J774A.1 cells were infected with indicated strains at an MOI of 100∶1. The number of intracellular bacteria per well after infection for 2 (A) or 24 (B) hrs was determined as described in methods; cells were thoroughly washed, lysed at the indicated time points, and then diluted and plated to determine CFU/ml. Bars represent the mean ±SD of a representative experiment performed in triplicate. This experiment was repeated two times with similar results. For panel A “*” indicates p<0. 003 compared to Schu S4. For panel B “*” indicates p<0.00001 compared to Schu S4 and “**”<0.007 compared to Δ fipAB.