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. 2011 Sep 8;6(9):e24611. doi: 10.1371/journal.pone.0024611

Table 2. Survival of fipA, and ΔfipAB mice after intranasal inoculation.

Strain Relevant genotype # of mice Inoculation dose (CFU)1 Days to Death2
Schu S4 4 10 5,5,5,5
BJM1068 ΔfipA 3 28 7,7,8
BJM1068 ΔfipA 3 280 6,7,8
BJM1068 ΔfipA 2 2800 5,6
BJM1069 ΔfipAB 4 7×107 Survived >30 days
BJM1076 ΔfipAB-fipA+B+ 3 10 6,6,7
BJM1076 ΔfipAB-fipA+B+ 3 100 6,6,6
BJM1076 ΔfipAB-fipA+B+ 3 1000 5,5,5
BJM1076 ΔfipAB-fipA+B+ 4 4.3×104 4,4,4,4
BJM1077 ΔfipAB-fipA+fipB C164A 4 8.8×107 Survived >30 days
BJM1078 ΔfipAB-fipA+fipB C167A 4 3.4×107 4,4,4,4
BJM1078 ΔfipAB-fipA+fipB C167A 4 3.4×104 8,8,8,8
BJM1078 ΔfipAB-fipA+fipB C167A 4 270 9,9,9,10
BJM1078 ΔfipAB-fipA+fipB C167A 4 27 9,10,10, >20 days
1

C57/BL6 mice were intranasally challenged with the indicated inoculum dose, which was confirmed by plating the inoculum.

2

Indicates the number of days after challenge that mice showed the first signs of irreversible mortality, and were euthanized. Mice were followed for a minimum of 20 days. Similar to the ΔfipAB mutant, mice similarly challenged with the ΔfipB mutant survive for more than 30 days without any signs of infection [14].