Table III.
Association of exogenous female hormone (HRT) use among postmenopausal women, stratified by smoking status and tumor site.
Exogenous Female Hormone Use |
|||||||
---|---|---|---|---|---|---|---|
Never (reference) |
≤ 5 years |
> 5 years |
|||||
Strata | Cases/ Controls | Cases/ Controls |
Crude OR (95% CI) |
Adjusted OR (95% CI) |
Cases/ Controls |
Crude OR (95% CI) |
Adjusted OR (95% CI) |
Smoking statusa | |||||||
Never smoker | 17/34 | 5/20 | 0.50 (0.16-1.58) | 0.49 (0.14-1.70) | 3/16 | 0.37 (0.10-1.46) | 0.65 (0.15-2.86) |
< 10 pack-years | 8/10 | 3/2 | 2.00 (0.26-15.48) | 3.37 (0.35-32.55) | 3/10 | 0.56 (0.05-3.39) | 1.84 (0.21-16.12) |
≥ 10 pack-years | 56/14 | 15/9 | 0.42 (0.15-1.15) | 0.59 (0.20-1.74) | 9/8 | 0.27 (0.09-0.84) | 0.31 (0.09-1.01) |
Tumor siteb | |||||||
Oral cavity | 36/58 | 10/31 | 0.52 (0.23-1.19) | 0.67 (0.27-1.66) | 8/34 | 0.38 (0.16-0.91) | 0.54 (0.21-1.43) |
Pharynx | 22/58 | 8/31 | 0.69 (0.27-1.77) | 1.29 (0.43-3.86) | 3/34 | 0.31 (0.08-1.14) | 0.31 (0.07-1.34) |
Larynx | 23/58 | 5/31 | 0.40 (0.14-1.15) | 0.60 (0.13-2.73) | 4/34 | 0.32 (0.10-1.00) | 0.27 (0.06-1.24) |
Abbreviations: OR = odds ratio; CI = confidence interval
Crude and adjusted models include the frequency-matched factor (age); adjusted model additionally includes highest level of education
Crude and adjusted models include the frequency-matched factor (age); adjusted model additionally includes