Table 2.
Effect of VIP-antagonist, L-NNA, AOAA, and PPG on the duration of inhibition during the 10 s of EFS at 3, 6, and 50 Hz.
| Duration of inhibition [s] | ||||
|---|---|---|---|---|
| Frequency | Control response | VIP-antagonist + L-NNA |
AOAA + PPG | VIP-antagonist + L-NNA + AOAA + PPG |
| 3 Hz | 6.0±0.3 | 3.8 ±0.3# | 6.6±0.5 | 4.5±0.5# |
| 6 Hz | 6.6±0.2 | 4.4±0.3# | 7.5±0.7 | 5.2±0.3# |
| 50 Hz | 4.9±0.6 | 3.5±0.4# | 5.9±0.6 | 3.9±0.4# |
#
Differs from control response and response with AOAA and PPG (p<0.05; ANOVA); there was no difference between VIP antagonists and L-NNA and the combination of all four antagonists.
VIP-antagonist
L-NNA: L-NG-nitro arginine
AOAA: aminooxyacetic acid
PPG: DL-propargylglycine